Buccal Micronucleus Cytome Assay- A Biomarker of Genotoxicity
نویسندگان
چکیده
منابع مشابه
Genetic damage in coal miners evaluated by buccal micronucleus cytome assay.
During coal mining activities, large quantities of coal dust, ashes, polycyclic aromatic hydrocarbons and metals are released into the environment. This complex mixture presents one of the most important occupational hazards for health of workers. The aim of the present study was to evaluate the genetic damage together with the presence of inorganic elements, in an exposed workers population to...
متن کاملRadiation risk assessment in professionals working in dental radiology area using buccal micronucleus cytome assay.
OBJECTIVE The aim of this study was to assess the incidence of micronuclei (MN) in buccal mucosal cells of professionals working in radiology area to determine the risk of stochastic effects of radiation. MATERIALS AND METHODS All the professionals and students working in King Khalid University - College of Dentistry radiology area were included in the Risk Group (RG = 27). The Control Group ...
متن کاملTesting chemical agents with the cytokinesis-block micronucleus cytome assay.
In order to evaluate the applicability of the cytokinesis-block micronucleus cytome assay in routine mutagenicity testing we investigated with this method different chemicals having different mechanisms of action: non-mutagens, direct-acting basealtering mutagens, direct-acting cross-linking mutagens, clastogens including a radiomimeti...
متن کاملMicronucleus cytome assay in the differential assessment of cytotoxicity and genotoxicity of cadmium and lead in Amietophrynus regularis
Amphibians are increasingly being used as bio-indicator of contamination in ecosystems due to their sensitivity to xenobiotics in the environment. Cadmium and lead compounds, ubiquitous mutagens and carcinogens, are capable of eliciting genome instability in adult toads which may enhance amphibian decline. Micronucleus cytome (MN-cyt) assay, a comprehensive cytogenetic test for the assessment o...
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Background & Objective: Micronucleus assay of buccal mucosa cells is a simple bio- monitoring method for diagnosing the genetic damages of toxic agents. The aim was to study the genotox...
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ژورنال
عنوان ژورنال: Journal of Molecular Biomarkers & Diagnosis
سال: 2015
ISSN: 2155-9929
DOI: 10.4172/2155-9929.1000236